Abstract High doses of sodium fluoride in bones lead to severe softening, by weakening interfacial properties between the inorganic minerals and the organic components, while leaving mineralization unchanged. This leads to reduction of microdamage and associated stress‐whitening pointing to a change in failure mode. Accordingly, elastic modulus, failure stress, and […]
bone
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Abstract CONTEXT: Bone mineral density (BMD) does not fully capture fracture risk as the majority of fractures occur in patients with osteopenia, suggesting that altered bone material properties and changes in microarchitecture may contribute to fracture risk. OBJECTIVE: This study aimed to evaluate the relationship between bone material strength (BMS), […]
Abstract Bone tissue mechanical properties are deemed a key component of bone strength, but their assessment requires invasive procedures. Here we validate a new instrument, a reference point indentation (RPI) instrument, for measuring these tissue properties in vivo. The RPI instrument performs bone microindentation testing (BMT) by inserting a probe […]